Found 448 of ic50 data for polymerid = 379 TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 0.240nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 0.427nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 0.584nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 1.87nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 2.70nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 3.60nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 5.60nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 6.13nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 11.7nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 12.4nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 12.8nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 13.5nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 14nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 20.2nMpH: 7.5 T: 2°CAssay Description:The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 29.5nMAssay Description:All reagents were diluted in 50 mM HEPES, 100 mM NaCl, 0.1% BSA, pH 7.4 supplemented with 0.05% CHAPS and allowed to equilibrate to room temperature ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 39.1nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 54.4nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 54.4nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 64.8nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 64.8nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 65.5nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 65.5nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 69.1nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 69.1nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 69.2nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 69.2nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 75.7nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 75.7nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 76.1nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 76.1nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 78.2nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 78.2nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 78.6nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 78.6nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 80.8nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 80.8nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 87.2nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 87.2nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 94.1nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 94.1nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 96.9nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 96.9nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 97.6nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 97.6nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.
US Patent
Dana-Farber Cancer Institute, Inc.
US Patent
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
